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See also: Crafting
- In the early Beta version of Don't Starve, the game used a "Research Points" system, instead of prototyping. When Wilson examines the Science Machine, he states that "It breaks down items into their scientific components", which is a leftover dialogue script from when the game used Research Points.
- The Science Machine appears at the top of the screen when the game "Autosaves".
- There appears to be rope turning the wheels on the machine, while no rope is needed to build it.
- The body of the Science Machine resembles the Companion Cube from Portal video game series.