Tooth Trap damage will not aggro nearby mobs, nor will it increase a player's naughtiness. Tooth traps are fireproof in all versions of the game. A Tooth Trap can be picked up and placed elsewhere at any time, regardless of having been triggered or not.
- Tooth Traps are ineffective against Lureplants and their Eyeplants; Eyeplants will eat Tooth Traps.
- Placing man-made Turf (after placing all the Tooth Traps) will prevent Eyeplants from spawning.
- A useful way to kill Pigs, or other mobs, without increasing Naughtiness, is to place food near the Tooth Traps (ideally so the trap will kill the victim before it reaches the food).
- Surrounding small groups of about 4 Berry Bushes with Walls and Tooth Traps allow farming Gobblers, which also protects unharvested Berries from them. When the Gobbler tries to exit, one of the Tooth Traps will kill it instantly.
- Alternatively, 1 Tooth Trap can be placed in front of a Berry Bush, instantly killing a Gobbler that spawns from the bush.
- Tooth Traps can be an effective way to kill Boss Monsters, or other tough enemies, if they are densely packed into one area.
- A "panic room" can be made with as little as 10 Tooth Traps. It should be made of Stone Walls, with as few entrances as possible; more Tooth Traps should be placed near the entrance, as opposed to evenly spread throughout the room. A panic room can be effective against Hound attacks.
- In Don't Starve Together, players' ghosts can reset Tooth Traps making it extremely useful when there's only one player left.
- The Tooth Trap used to cost 100 points under the old Research Points system.